Pathophysiology for Advanced Nursing

NR.502 4 credits Semester 1

Course Overview

Pathophysiology for Advanced Nursing explores the mechanisms of disease and dysfunction across organ systems. This course provides the scientific foundation nurses need to understand patient presentations, anticipate complications, and implement appropriate interventions. Students examine cellular pathology, inflammatory and immune responses, fluid and electrolyte imbalances, and system-specific diseases. Topics include cardiovascular disorders, respiratory dysfunction, renal failure, endocrine dysfunction, and neurological conditions. The emphasis is on applying pathophysiologic concepts to clinical nursing practice and patient education.

Learning Objectives

  • Apply cellular and tissue injury mechanisms to explain clinical manifestations of disease
  • Analyze inflammatory and immune responses including acute and chronic inflammation
  • Understand fluid and electrolyte balance disturbances and their clinical consequences
  • Examine cardiovascular, respiratory, renal, and endocrine pathophysiology
  • Connect pathophysiologic changes to assessment findings and nursing interventions
  • Predict disease progression and complications based on pathophysiologic principles

Lecture Topics

  • Week 1: Cell Injury, Adaptation, and Death
  • Week 1: Inflammation and Inflammatory Mediators
  • Week 2: Immunity and Immune Response Disorders
  • Week 2: Fluid and Electrolyte Balance and Imbalances
  • Week 3: Acid-Base Disturbances and Compensation Mechanisms
  • Week 4: Cardiovascular Pathophysiology - Hypertension and Heart Disease
  • Week 4: Cardiac Arrhythmias and Acute Coronary Syndrome
  • Week 5: Respiratory Pathophysiology - Asthma, COPD, and Acute Respiratory Distress
  • Week 5: Renal Function and Acute/Chronic Kidney Disease
  • Week 6: Endocrine Disorders - Diabetes and Thyroid Dysfunction
  • Week 7: Neurological Pathophysiology - Stroke and Intracranial Pressure
  • Week 8: Integrating Pathophysiology into Nursing Assessment and Care

Course Quiz

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Flashcards

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Resources

Pathophysiology: The Biologic Basis for Disease (McCance & Huether)

Comprehensive textbook with detailed pathophysiologic mechanisms across all systems and disease states.

Required

Interactive Pathophysiology Case Studies

Clinical scenarios linking pathophysiology to patient presentations and nursing care planning.

Required

Electrolyte and Acid-Base Flashcard Deck

Visual aids and mnemonics for mastering fluid, electrolyte, and pH disturbances.

Free

Khan Academy: Pathophysiology Video Series

Clear explanations of disease mechanisms with animations and real-world clinical correlations.

Free